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M1 macrophages are typically induced by signals such as interferon-gamma (IFN-) or lipopolysaccharide (LPS) and they highly express reactive oxygen species (ROS) and nitric oxide while secreting pro-inflammatory cytokines like TNF- and IL-12 thereby contributing to pathogen clearance and anti-tumor immunity (31, 32)

[24] Some enzymes contained in barley or synthesized during germination can have antioxidant activity

Glutathione is a natural helper already inside your body, working like a gentle cleaner that keeps things tidy at the cell level

Furthermore, bladder tumors in mice supplemented with glutamine showed lower PD-L1 levels than control tumors 148

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