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doi:10.1007/978-0-387-46401-5_1

While the experimental models employed in PD have shown connections to human health, it remains a daunting task to translate mechanisms of action observed in in vitro and in vivo studies of natural compounds to clinical outcomes in human trials, where it is a critical step in drug development

GABA secreted by histaminergic neurons also downregulates histamine signaling

Leafy Greens: Kale, spinach, mustard greens, bok choy, Swiss chard, collards, and watercress are all so rich in antioxidants that you often feel healthier just by biting into them

Moving beyond the traditional fragmented perspectives that have limited our understanding and management of the disease, our analysis of current information on ME/CFS represents a significant paradigm shift by synthesising the diseases multifactorial origins into a cohesive model