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however, more research is needed

Optimal combinations of vitamins B1, B2, B6, L-methylfolate, methylcobalamin (B12), C, D, natural vitamin E complex, lutein, zeaxanthin, alpha-lipoic acid, and n-acetylcysteine are identified for protecting the retina and choroid

Dosing and Monitoring Clinicians tailor methods of treatment for each patient by monitoring their response to treatment and the goals of treatment, starting patients on a low dose of methadone and increasing it until the patient stabilizes from withdrawal and reports reduced or absent cravings (90)