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These receptors sit on the surface of adipocytes (fat cells), and when activated, they trigger a cascade of intracellular signals that ultimately activate hormone-sensitive lipase

If you damage your parietal cells (for any reason) then you will also limit your ability to absorb vitamin B12

3,4 Serum B 12 levels below 100 pg/mL are reported to have specificity approaching 90% for diagnosing clinically-manifest deficiency

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Candidates typically have weight-related health concerns or difficulty controlling appetite