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A 107 , 92089220 (2003) Rignanese, G., Angelis, F.D., Melchionna, S., Vita, A.D.: Glutathione transferase: a first-principles study of the active site

In rat permanent MCA occlusion, infusion of ebselen, starting 45 min before and maintained 4 h after the occlusion, reduced cerebral cortical damage by 28%

Conversely, when oxidative challenges exceed physiological levels, they can disrupt redox signaling and cause oxidative damage to biomolecules, termed oxidative distress