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Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition

Fish intake was evaluated in servings per week

A synergistic effect of paclitaxel (5 nM) and arsenic trioxide (1 M) was observed in inhibiting proliferation and inducing apoptosis of Jurkat T-cell ALL cells, which was related to the increased phosphorylation of Cdk1 and formation of the inhibitory spindle checkpoint complex BubR1/Cdc20

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