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Given the poor bioavailability of oral NAD+ and its precursor vitamins through supplements (and why most wellness supplements have limited benefit), IV or subcutaneous routes are necessary to achieve the serum concentrations observed in the published research

Peptide bioregulation of aging: results and prospects. Biogerontology 11.2 (2010): 139-149

Pravastatin did not affect sICAM-1, sVCAM-1, or E-selectin levels in MetS patients, whereas simvastatin lowered PAI-1 activity

avium ), a bacteria known to cause blood-based infections

Many patients repeat cycles 2-4 times per year as part of a comprehensive longevity program