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Homocysteine and vascular disease

Meta-analysis of 82 trials involving 7,469 treatments documented the following safety data: Most Common Side Effects: Ear barotrauma: 30% incidence (mostly mild ear discomfort managed with equalization techniques) Oxygen toxicity seizures: 0.25-6 per 10,000 sessionsextremely rare Transient visual changes: Temporary and reversible Mild headaches: Usually resolve with hydration Sinus barotrauma: Pressure-related discomfort Serious Adverse Events: Multiple large studies involving 80-248 patient cohorts reported zero life-threatening complications