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[26] [27] Niacin commonly causes flushing (occurring in up to 80% of patients with immediate-release formulations), pruritus, and gastrointestinal upset

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The Head-Up Tilt table test as a measure of autonomic functioning among patients with myalgic Encephalomyelitis/Chronic fatigue syndrome

Both concluded that acupuncture was effective and safe, significantly reducing total NIH-CPSI scores compared to sham or medical treatment, and should be considered as a treatment option