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343 Evexomostat (SDX-7320), which irreversibly binds METAP2 and regulates insulin, leptin, and adiponectin downstream, was one of the first drugs developed for cancer patients with metabolic complications

Berhane T, Vetrhus M, Hausken T, Olafsson S, Sondenaa K (2006) Pain attacks in non-complicated and complicated gallstone disease have a characteristic pattern and are accompanied by dyspepsia in most patients: the results of a prospective study

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Liposomes played a critical role in this innovation by protecting the fragile mRNA and facilitating its delivery into cells

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