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Supplementation with GSH is generally ineffective at increasing cellular glutathione levels because most human cells cannot uptake extracellular GSH due to the lack of the membrane-bound ectoenzyme -glutamyltranspeptidase (-GT) or due to an unfavorable concentration gradient across the cell membrane 10,16

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease

Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntingtons disease

Mucoadhesive nanomedicines: characterization and modulation of mucoadhesion at the nanoscale

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS