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Current investigations are also evidencing the role exerted by other key signalling molecules, such as glycogen synthase kinase 3 and beta-catenin, in the cross-talk of estrogen receptors and IGF-I receptors in neural cells[345]

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TB-500 is a synthetic analog of Thymosin Beta 4, a naturally occurring peptide found in nearly every cell, with the highest concentrations in blood platelets and wound healing fluid