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Biosynthesis, recycling and degradation in mammals

HsuYHWuCHChiuCJChenWTChangYCWabitschMet al

Starting Dose 0.3 mg In the phase 2 weight study, dosing started low at 0.3 mg weekly and was raised every 2 weeks to reduce nausea [1]

Mol Aspects Med 30:2941 Zaman GJ, Lankelma J, Tellingen O, Beijnen J, Dekker H, Paulusma C, Oude Elferink RP, Baas F, Borst P (1995) Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein