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Certain B vitamins, particularly vitamin B6 and B12, are excreted through the kidneys, and accumulation may occur in severe renal dysfunction

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Vitamin B12 deficiency has emerged in recent years as one of the major factors that may be of importance for its development and progression.Vitamin B12 is an important nutrient necessary for numerous metabolic activities that keep our bodies running smoothly, including fat metabolism, thereby making any shortage far-reaching in its consequences on liver health