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Estrogen-induced gene expression is one example of how this pathway influences gene regulation (Hao et al., 2018) The essential mechanism relies on the catalytic function of 8-oxoguanine DNA glycosylase-1 (OGG1) and the structural modifications induced by topoisomerase IIb on the promoter

Chronic psychosocial stress in mice elevates ROS in GCs, impairing follicular development and promoting apoptosis [24, 98]

Emerging evidence indicates that the KD modulates the composition of gut microbiota

TAMs are responsible for the release of epidermal growth factor (EGF) in OC, which directly activates the EGF receptor (R)-ERK pathway (101)

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