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Look AHEAD Research Group Effect of 1 year of an intentional weight loss intervention on bone mineral density in type 2 diabetes: results from the Look AHEAD randomized trial J Bone Miner Res 27 3: 619-27

In turn, oxalate overload suppresses PPAR transcription and the expression of its target genes controlling FAO (CPT1), leading to impaired mitochondrial fatty acid utilization and lipotoxicity, as well as the upregulation of MASH-promoting chemokines (CCL2), monocyte chemotaxis, hepatic inflammation and fibrosis

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Eur J Gastroenterol Hepatol 13:11891193 Padmanabhan P, Grosse J, Asad AB, Radda GK, Golay X (2013) Gastrointestinal transit measurements in mice with 99mTc-DTPA-labeled activated charcoal using NanoSPECT-CT