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Administration of doxycycline (2 mg/kg) in the drinking water in mice challenged with intratracheal LPS, significantly decreased the number of neutrophils and shed syndecan-1 in BALF

Jochen Zeil (1949-) was born in Gauting, Germany

3 ): Here, R red and R ox are the fluorescence ratios under fully reduced (DTT-treated) and fully oxidized (H2O2-treated) conditions, respectively, while I 488red and I 488ox are the fluorescence intensities at 488 nm in reduced and oxidized states

Given that hypoxia changes oxygen extraction, delivery and uptake, as well as altering lactate kinetics and buffering, we would caution against the indiscriminate use of sea-level ergogenic aids until more hypoxia-based data are generated