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Fe 3+ in the plasma can bind to transferrin receptor 1 (TFR1) after loading onto the TF, which is then endocytosed into the cytoplasm

Shakhristova, E

Gut microbiota dysbiosis negatively affects the regulation of anti-inflammatory and immune system responses and appears to be associated with autoimmune diseases, inflammation, and some types of cancer (189, 236, 237)

However, despite the advantages of lipid-based nanodrug carriers, they still face challenges related to solubility, stability, and aggregation ( Polymer-based nanodrug carriers are another widely used carrier system, typically made from synthetic or natural polymer materials such as polylactic acid (PLA), polyethylene glycol (PEG), and poly (D,L-lactic-co-glycolic acid) (PLGA) (Ibrahim et al., 2022

To do so, we probed the ability of both WT and ATG7 knockout (ATG7, hereafter) HeLa cells to form LC3B puncta