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By replacing the PSMA-targeting moiety with ligands specific to other tumor-associated antigens (e.g., HER2, EGFR, or folate receptor), similar nano-PROTACs could be developed for other cancers

coli pathogenesis mediated by microbiome metabolites

Ito A, Kawaguchi Y, Lai CH, Kovacs JJ, Higashimoto Y, Appella E, et al

Cagrilintide monotherapy produced 10.8% mean body weight reduction at 26 weeks in the REWIND Phase 2 trial, while survodutide achieved 12.9% reduction at the highest evaluated dose (4.8mg weekly) in Phase 2 studies