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Description

Under oxidative conditions, sulfide could react with oxidized thiol groups, particularly sulfenic acids

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Even when absorbed, its hydrophobic nature often leads to efflux back into the intestinal lumen via the P-glycoprotein transporter, which is highly expressed in the intestine (Metzler et al., 2013)

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As for the metabolic features, therapy-refractory cancer cells in certain statuses could perform surprisingly sensitive to ferroptosis [58, 104, 105]

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That is both their strength and their limitation

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