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As absorption is reduced, body stores become low and a deficiency occurs Underlying diseases most commonly include: IBD (inflammatory bowel disease) Intestinal cancer (especially small cell lymphoma) Liver disease Pancreatitis and other pancreatic diseases Symptoms of low B12 levels Typically found in middle-aged or older cats that present with: Weight loss Diarrhea Vomiting Anorexia Thickened intestines In humans, B12 deficiency may also be associated with dementia, cardiovascular disease, and a certain type of anemia, although these are not specifically recognized problems in cats

Initial screening primarily focuses on abnormalities in copper metabolism, including serum ceruloplasmin levels and baseline 24-hour urinary copper excretion

Nutrient depletion will result in elevated AMP/ATP ratio and lowered ATP levels

This episode is a must listen for anyone with hypothyroidism, hashimotos, graves disease or any autoimmune disease

Epigenetic modifications refer to the regulation of gene expression through chemical modifications without altering the DNA sequence