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Once-weekly cagrilintide for weight management in people with overweight and obesity: A multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial

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Current approaches, including pharmacological and behavioral interventions, often focus on mitigating symptoms rather than addressing the underlying mechanisms of damage

In the absence of changes in cell viability of the bEnd.3 endothelial cell line, bovine serum albumin and advanced glycation end-products contribute to an elevation in endothelial cell barrier permeability and a significant and prolonged oxidative stress response

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