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Subjects were selected from participant sites that prescribe ALCAR 3 or 1.5 g/day per OS as per clinical practice

Dilute an appropriate amount sample with a 1:1 ratio of Binding Buffer before applying to the purification column

Anti-inflammatory diet Reduce inflammatory foods : Processed foods Excess sugar Refined carbohydrates Trans fats Increase anti-inflammatory foods : Omega-3 rich fish Leafy greens Berries Turmeric, ginger Olive oil Supplements : Omega-3s: 2-3g EPA/DHA daily Vitamin D: 2,000-5,000 IU daily Curcumin: 500-1,000mg daily Weight management Every pound matters : Each pound of body weight = 4 pounds of pressure on knee joints

Reduced Inflammation Some vitamins, such as Vitamin D and Omega-3 fatty acids, have been shown to have anti-inflammatory properties that can help reduce inflammation in the body

110 However, the role of the UPS is tissue specific, e.g., in muscle cells from insulin-resistant individuals, proteasome activity is increased, contributing to muscle protein degradation and atrophy