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The subretinal injection can be introduced via pars plana. Interested parties, including the manufacturer of Luxturna, recommended CPT code 67036 (Vitrectomy, mechanical, pars plana approach) for the administration of the gene therapy

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The risk of death from autologous fat transfer to the gluteal region is estimated at 1:3000

Neither category of side effect is amplified by the other in any documented way

However, several factors affect the ability of CEF in achieving this brain tissue concentration such as expression or inhibition of P-glycoprotein (P-gp)