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Nature 426 , 172176 (2003)

However, the ~16% difference in elevation of muscle carnosine between the two formulations did not reach statistical significance, perhaps due to the small sample size or the short supplementation period

Its key physiological functions include: Nitrogen transport between tissues Acid-base regulation Supporting gluconeogenesis Serving as a precursor to nucleotide bases Boosting the antioxidant glutathione (Cruzat et al., 2018, Nutrients ) Glutamines Role in Muscle Growth and Recovery L-Glutamine plays a powerful role as a signaling molecule in stimulating anabolic pathways such as muscle protein synthesis and cell growth , while inhibiting catabolic pathways including protein degradation and apoptosis (Newsholme et al., 2003, The Journal of Nutrition )