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10.19540/j.cnki.cjcmm.2017.0153 Summary Keywords rheumatoid arthritis, total glucosides of paeony, collagen-induced arthritis, metabolomics, network pharmacology, intestinal mucosal immunity Citation Xu R, Peng J, Ma Z, Xie K, Li M, Wang Q, Guo X, Nan N, Wang S, Li J, Xu J and Gong M (2023) Prolonged administration of total glucosides of paeony improves intestinal immune imbalance and epithelial barrier damage in collagen-induced arthritis rats based on metabolomics-network pharmacology integrated analysis

The medial prefrontal cortex (mPFC), which can be subdivided into the prelimbic (PL) and infralimbic (IL) cortices is essential for higher-order cognitive functions such as decision-making, working memory, and behavioral regulation [20]

This is associated with an inflammatory phenotype and can promote neurodegeneration

This potency is useful for research protocols that require a maximal GH stimulus for instance, studies examining downstream IGF-1 production, hepatic GH receptor signaling, or somatotropic feedback loop dynamics

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