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Docking of SlGSTU5 (receptor) with safeners (ligand) was carried out using autodock_vina_1_1_2_win32.msi [50] and MGLTools_win32_1.5.6 [51]

The correlation coefficient (CC) of 9 in the two different conformations is in the 0.670.71 range, close to the CCs of the FAD cofactor in each subunit (CC = 0.730.74)

A population of cells with stem cell properties (glioblastoma stem cells, GSCs) drives the initiation and progression of GBM and is localized in specialized microenvironments which support their behavior