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Which could make you question, is B12 the issue, or is it an imbalance in the skin microbiome thats reacting to high-dose B12

Crucially, the obesity paradox is likely heavily confounded by two factors: (1) whether weight loss is intentional, and (2) the use of the BMI metric, which poorly reflects the contribution of body composition towards body weight in older adults [15, 34]

The regulatory picture matters enormously here, and it is frequently blurred by vendor copy: Cosmetic ingredient

Huberman went on to acknowledge the potential of BPC-157 but stresses the need for more robust human clinical trials to validate its use in injury recovery and broader applications for longevity