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doi: 10.1182/blood-2006-12-063636 48 TsujimotoHOnoSMajimaTKawarabayashiNTakayamaEKinoshitaMet al

428,429 HSPs are induced in response to various CNS pathologies, including neurodegenerative diseases, ischemia, and epilepsy, where they play a neuroprotective role by preventing protein aggregation and misfolding