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Furthermore, it has been found in humans and animals that nicotine enhances the learning ability (Poorthuis et al., 2009), improves neuronal plasticity in the hippocampus (Motaghinejad et al., 2016), and can treat excitotoxicity at low concentrations (Sieber, 2012)

Supplementation is a gradual process

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Beyond that, you could experience longer-term cognitive and neurological disturbances such as potential nerve damage

Slowing down the dose escalation is always preferable to abandoning the protocol entirely