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For example, in a classic peritoneal metastasis model of human ovarian cancer, researchers delivered daily intraperitoneal administration at 20 mg/kg/d of the product and found that it effectively inhibited the distant metastasis and rapid proliferation of HeyA8 ovarian cancer cells

Furthermore, researchers discovered that osmundacetone (OSC), a bioactive phenolic compound derived from Phellinus igniarius, exhibited regulatory effects on the immune microenvironment, as confirmed by downregulation of GLUD1 expression upon OSC treatment [211]

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Acute insults often cause multi-level damage including structural damage, metabolic stress and impairment of molecular homoeostasis, which trigger widespread homoeostatic failure

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