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All four groups of mice underwent most of the hepatectomy (24 h water fasting before surgery), and samples were taken after 0, 1, 3, and 7 days of postoperative anesthesia (intraperitoneal injection of 1% pentobarbital sodium (7 L/g body weight), respectively (24 h water fasting before specimen collection)

Our results indicated that neither GHK nor GHK-Cu showed cytotoxic activity after 72 h exposure to HaCaT cells

Do not mix with other medicinal products in the same syringe or infusion solution unless compatibility has been established

All these structural and functional changes have direct clinical consequences, leading to the acceleration of the general aging process, but also to some pathological phenomena, associated with the increase of the capillary permeability, impairment of the blood cell function, etc

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