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In a thirteen-week study, notable biochemical and histopathological changes were observed, but they were not of toxicological significance as PQQ levels remained within safe ranges, showing no dose-dependent toxicity (Liang et al., 2015)

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and 6) Ferrostatin-1 (Fer-1) group: cells pre-treated with 2 M Fer-1 for 30 min ( 2.6 Network pharmacology analysis 2.6.1 Identification of potential targets of AB4 and SALI Potential targets of AB4 were obtained from four databases: Comparative Toxicogenomics ( GeneCards ( SwissTargetPredict ( and TargetNet ( databases

There is evidence to suggest that presbycusis includes the accumulation of cochlear damage from various sources, and especially that of noise exposure