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At the same time, smoking induces systemic and local oxidative stress, impairing mitochondrial integrity and disrupting estrogen synthesis by downregulating aromatase and steroidogenic transport proteins

Radiation necrosis (RN) may occur from months to years following treatment, affecting a reported 324% of patients [13]

4.5 Copper Copper (Cu) plays two main roles: it promotes melanogenesis and provides physiological protection against oxidative stress by participating in the destruction of free radicals through the formation of superoxide dismutase, which catalyses the dismutation of reactive oxygen species to oxygen (O 2 ) or H 2 O 2

aegypti [13]

Stop the reaction by adding 0.6 ml of the 200 mM EDTA stock solution