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Pluvicto is a targeted radioligand therapy for adult patients who have already undergone other anti-cancer treatments

In this work, we develop a peptide-ferriporphyrin conjugate with tumour microenvironment specific activation for improved tumor penetration and endocytosis, which enables effective inhibition of GPX4 due to the assembly enhanced binding (AEB) effect, ultimately improving its anticancer activity via ferroptosis (Fig

[30] Side effects [edit] Folinic acid should not be administered intrathecally

To view a copy of this license, visit About this article Cite this article Kelly, R.A., Leedale, J., Calleja, D

Inadequate water intake can lead to dehydration and a host of unwanted effects: headaches, constipation, reduced athletic performance and recovery, reduced mood and cognitive performance and confusion/delirium (Popkin et al