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Oxidative Stress Environmental pollutants generate free radicals that damage skin cells and promote pigmentation

However, Sp-L-DOPA combination showed consistent negative geotaxis even during the wearing-off phase, representing substantial alleviation of L-DOPA toxicity and promotion of enhanced mitochondrial and cellular health in dopaminergic neurons

Individual toxicities (excluding SMNs discussed below) and key genomic associations are summarized in Supplementary Material 1, Supplementary Table 2 and Fig