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Oxaliplatin downregulates expression of potassium channel Kv2.2 in the somatosensory cortex, thereby requiring a smaller stimulus for neuronal firing (Thibault et al., 2012)

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1a, 2g, h), while the side chain points into the core of the receptor and is surrounded by hydrophobic amino acids, namely C130 3.32 , L133 3.35 , I185 4.61 , L197 5.34 , F261 6.51 , and L288 7.39