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Description

Ontario Health Technology Assessment Series 2013;13:124

Yuan X, Bhat OM, Meng N, Lohner H, Li PL

5-Amino-1MQ is a small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor researched in cellular metabolism and energy homeostasis models

To rule out the possibility that the cleavage of GFP-Atg8, the formation of GFP-Atg8 puncta, and the increase of the Atg8PE protein are caused by a non-autophagic process, we deleted the gene encoding the autophagy core machinery protein Atg1