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In addition, nasal sprays provide precise and effective distribution to the nasal passages, where the peptides might act systemically or locally (for example, in disorders involving the nose or brain) [1]

This modification extends the peptide's half-life from minutes (native IGF-1) to several hours and enhances systemic bioavailability [2]

IGF-1 LR3 is a modified, longer-acting version of IGF-1, which allows for extended stimulation of growth receptors

The Journal of clinical endocrinology and metabolism, 89(5), 22902300