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doi:10.1016/j.bioactmat.2024.08.006 149

Oxidative modification of low-density lipoprotein (LDL) cholesterol forms oxidized LDL (oxLDL), which is highly atherogenic [68]

DOI: 10.1210/jc.2005-1536 Ionescu M & Frohman LA (2006) Pulsatile Secretion of GH Persists During Continuous Stimulation by CJC-1295 J Clin Endocrinol Metab 91(12):47924797

This system also enhanced mitochondrial energy metabolism by upregulating cytochrome c oxidase subunit IV (COX IV) expression, while suppressing -secretase 1 (BACE1) and amyloid precursor protein (APP) overexpression, ultimately reducing A production and aggregation