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Recently, it has been reported 66 that the yield of membrane proteins expression in mammalian cells can vary by up to 5 folds when fused with different GFP variants

"COPD: help your patients breathe easier." RN (2008)71(1):21-6

Figure 3 Among them, PRIMA-1 and PRIMA-1Met (APR246, eprenetapopt) have emerged as the first structural reactivators of mutant p53 variants recovering its transcriptional activity by covalent binding cysteines within the core domain (65)

"N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility." Expert Opin Biol Ther

The identified genes are ones known to govern oxidative stress and neuronal ATP levels, suggesting for the first time that mitochondrial genes might be altered in tissue samples from human patients