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November 16, 2023

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In case of colorectal cancer, miR-548b overexpression can suppress cell proliferation by targeting Wnt2 (Xu et al., 2020)

Thus, therapies that target the CXCL12/CXCR4 and HIF pathways, as well as Treg, may be advantageous for this subset of breast tumors that are less likely to respond to standard chemotherapy