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Specifically, protein carbonyl levels showed a statistically significant increase even at the 1-h time point, and this increase was almost maintained at 3, 6, 12 and 24 h, especially in response to higher concentrations of uric acid

Hengstler JG, Lange J, Kett A, Dornhofer N, Meinert R, Arand M et al

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However, exogenous application of JA exhibited efficient results on detoxification of MG, as evident by a correlation between reduced MG concentration and amplifying Gly enzyme activities, which thereafter protected cells from MG induced toxicity