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[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Gomes AP, et al

Astragaloside IV ameliorates myocardial injury in diabetic rats by suppressing CD36-mediated ferroptosis and reducing lipid deposition

However, it is important to note that curcumin has also been identified as a PAINS, exhibiting behaviors such as redox cycling, metal chelation, aggregation, and fluorescence interference that can artificially inflate its apparent bioactivity in vitro (Nelson et al., 2017)

Anyone interested in the regulatory outcome should monitor the FDA's formal rulemaking process, which must follow the advisory committee recommendation before any change takes legal effect