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El desarrollo de la artritis reumatoide se basa en una predisposicin gentica, como los alelos HLA-DR4, que crean anticuerpos contra las protenas citrulinadas, y en factores desencadenantes ambientales, como las infecciones o el tabaquismo [8]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Heidari R, Babaei H, Eghbal M

Smith EF, Shaw PJ, De Vos KJ

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