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Springer London

Transcriptional gene network involved in drought stress response: application for crop breeding in the context of climate change

118 (1): e139e150

Notably, serum-based fibrosis scores (e.g., ELF test incorporating HA, PIIINP, TIMP-1) have already gained FDA breakthrough designation and are integrated into ongoing phase II/III clinical trials for MASLD drug development [341]

One of the inflammatory mediators released during liver damage, TNF- participates in the inflammatory cascade, triggering processes such as hepatocyte dysfunction, necrosis, and apoptosis