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The mitochondrial pyruvate carrier (MPC) regulates the entry of glycolytic pyruvate into the mitochondria, serving as a key node linking glycolysis to OXPHOS [51]

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2374-C TARGETING CHRONIC VEGF-C SIGNALING MITIGATES DISEASE PROGRESSION IN NON-ALCOHOLIC STEATOHEPATITIS Jason Eng 1,2 , Seock-Won Youn 1 , Bhairavi Swaminathan 1 , Rahul Vadakath 1 and Jan Kitajewski 1,3 , (1)University of Illinois at Chicago, (2)Cleveland Clinic Foundation, (3)University of Illinois Cancer Center Background: The sinusoidal endothelial cells (LSECs) are critical regulators of homeostasis within the liver