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Misalignment of the joints increases uneven stress and friction

This GLY level is roughly equivalent to the 133 mM/kg/d dose used in human dietary intervention studies (Reference Sekhar, Patel and Guthikonda21,Reference Nguyen, Hsu and Jahoor23)

doi: 10.1016/S1350-9462(03)00050-8 13 LimJCVaghefiELiBNye-WoodMGDonaldsonPJ

The calibration and validation results show that both in the control and the rd1 case, the model produces output for [GSH] and [GSSG] approximating trends in the experimental data, and there is notable uncertainty in the estimated parameters

These changes, on the other hand, are reversible and specific enzymes catalyze their removal