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Endogenous microRNAs (miRNAs/miRs) are a perennial research hotspot in the field of fibrotic disorders because of their involvement in regulating the Smad3-mediated TGF-/Smads pathway

A common treatment for depression is the use of antidepressants

doi: 10.1016/j.lfs.2023.121877 175 Banham-HallEClatworthyMROkkenhaugK

it is especially true for autoimmune connective tissue diseases (e.g., SLE), where some off-label therapies (e.g., rituximab) seem to work in selected cases in the everyday clinical routine but failed to show significant differences over placebo in clinical trials ( Despite the fact that there are many differences in the pathogenesis of systemic autoimmune diseases, many aspects are similar, leading to common molecular targets, like type I IFN/IFN receptor, IL-17, GM-CSF receptor, BAFF, CD40/40L, or JAK/STAT ( Table 2 )

Leaky gut supplements should be generally safe for most healthy adults