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Opioids produce a diverse spectrum of centrally- and peripherally-mediated responses, including respiratory depression, nausea, sedation, euphoria or dysphoria, decreased gastrointestinal motility, and itching (1)

Via glycolysis, glucose is metabolized to pyruvate, which can be oxidized by the TCA cycle to generate ATP

These findings uncover ANPEP as a valuable target for therapeutic interventions to treat patients with liver cancer experiencing chronic stress

It plays a critical role in regulating gene transcription and expression in neurons and glial cells

Monocytes/macrophages have been found to massively infiltrate synovial membranes 51 and be central to the pathophysiology of inflammation